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Friday, August 5, 2011

Meningitis


Meningitis
Aetiology 
n      A) Bacterial:
n      Three Iry pathogens
n      N. meningitidis.
n      Haemophilus influenza.
n      Strept. pneumoniae.
n      -    Mycobacterium T.B------chronic
n      Coliforms.
n      In neonates
n      B. haemolytic streptococci.
n      Listeria monocytogenes.
n      Salmonella.
n      Pseudomonas.

n      Spirochaetes
n      Leptospira.
n      Treponema pallidum.
n      Borrelia.
n      B) Viral:
n      Entero-viruses: Echo, Polio.
n      Herpes, Varicella-zoster.
n      Adeno-viruses.
n      HIV.
n      C) Fungal:
n      Cryptococcus neoformans.
n      Candida.
n      Aspergillus.
n      Mucor.
n      D) Amoeba:
n      Naegleria.

n      Investigations:
n      CSF and blood culture on chocolate or blood agar in presence of 5 – 10% Co2, before start of antibiotics.
n      Blood culture.
n      Nasopharyngeal swab culture: may be the only way to isolate meningeococci.
n      Antibiotic sensitivity tests.
n      Latex agglutination for microbial antigen.
n      PCR-DNA of microorganisms e.g. TB DNA.
 Need to know more read Lectures on applied clinical microbiology
http://www.amazon.com/Lectures-applied-clinical-microbiology-ebook/dp/B004Y0XF54

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