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Wednesday, October 26, 2011

Innate Immune Response to Pathogens and Recent Advances in Microbiology Researches

An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own healthy cells and tissues in order to function properly. Detection is complicated as pathogens can evolve rapidly, and adapt to avoid the immune system and allow the pathogens to successfully infect their hosts.
To survive this challenge, multiple mechanisms evolved that recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess enzyme systems that protect against viral infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include antimicrobial peptides called defensins, phagocytosis, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms. The typical vertebrate immune system consists of many types of proteins, cells, organs, and tissues that interact in an elaborate and dynamic network. As part of this more complex immune response, the human immune system adapts over time to recognize specific pathogens more efficiently. This adaptation process is referred to as "adaptive immunity" or "acquired immunity" and creates immunological memory. The following chapters will discuss various mechanisms of immune response to pathogens based on laboratory evidence studies.
Innate Immune Response to Pathogens and Recent Advances in Microbiology Researches [Kindle Edition]

Chapter One: Immune response to Pathogen
Chapter Two: Interleukin 6 response in Children with Echerichia coli 6 associated Urinary tract Infection, One centre Study.
Chapter Three: Natural Killer Activity and Mycobacterium tuberculosis Infection
Chapter Four: Study of Interleukin 12-Gamma interferon Axis and Natural Killer Cells in Acute Viralhepatitis
Chapter Five: Study of antioxidants' Enzymes Kinetics, Superoxide

dismutase, Glutathione peroxidase and Catalase, in Neonatal Sepsis
Chapter Six: TNFα and IFNγ, EARLY KINETICS DURING FEVER IN 64 PATIENTS WITH HAEMATOLOGICAL MALIGNANCIES AND NEUTROPENIA

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